From Hardlimit
To add on here, you can use the Are We Anti-Cheat Yet? site to track which games are not working due to anti-cheat. In my experience it’s extremely rare for “Linux” (aka Wine/DXVK/VKD3D/et al) to not support arbitrary games. If a game is not working on Linux it’s almost certainly because of an anti-cheat or some bloated/obscure DRM telling Linux “no you cannot run this”.
Sadly anti cheat is much cheaper for devs than fast manual moderation. And a cheater infested game dies off much faster.
And client-side anticheat solutions aren’t great at preventing cheating, anyways. Anticheats are still bypassed by smart software design or by using third-party devices, like the Cronus. COD’s intrusive newer anticheat didn’t stop hacking in ranked play this past year, for instance.
I recommend this video from Serious, who has experience with modded clients and developed a patch to secure BO3 when it was unsafe to play.
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Just making it harder to cheat and having a way to patch it and instantly get a wave of bans does discourage cheating quite a bit. Especially in paid games. You will never get rid of cheating completely, but cutting down on it and discouraging it is the name of the game.